Spinal cord regeneration: new experimental approach
نویسندگان
چکیده
منابع مشابه
Clinical and Experimental Advances in Regeneration of Spinal Cord Injury
Spinal cord injury (SCI) is one of the major disabilities dealt with in clinical rehabilitation settings and is multifactorial in that the patients suffer from motor and sensory impairments as well as many other complications throughout their lifetimes. Many clinical trials have been documented during the last two decades to restore damaged spinal cords. However, only a few pharmacological ther...
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Neurological rehabilitation is expanding its scope to include restoration of function through regeneration. However, this complex task will require multi-stage interventions, some easier to achieve than others. Of repair strategies on the horizon, harnessing the potential of neural stem cells already present in the CNS and placed there by transplantation appears promising. In fact, using stem c...
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Myelin is a potent inhibitor of axon regeneration, but has been viewed as just one of many factors that prevent regeneration after injury. So it comes as a surprise that immunization against myelin has been found to allow extensive axon regeneration after injury, without apparent autoimmune-induced demyelination.
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Neurons in the peripheral nervous system (PNS) have the capability to regenerate after injury or disease while central nervous system (CNS) neurons do not. Elucidation of the reasons for this difference in regenerative ability is crucial to developing treatments for sufferers of CNS disorders, injury, and stroke. Therefore, my lab investigates molecular mechanisms underlying neuronal repair, ax...
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ژورنال
عنوان ژورنال: Spinal Cord
سال: 1988
ISSN: 1362-4393,1476-5624
DOI: 10.1038/sc.1988.46